Discovery leads to innovation. Innovation usually leads to changes in processes. But that doesn’t always equate to better. Or not necessarily as a replacement.
You may have seen a commercial or two for a commercial product where a walking and talking white box depicts the ease and comfort for checking for colorectal cancer at home. The insinuation is that anyone can simply send in a sample of their “#2” and find out if they have anything to worry about regarding cancer in the lower gastrointestinal tract.
But at what cost is this substitute for the gold standard of colonoscopy screening actually to the patient? What are the accuracy comparisons? What to make of a positive or negative result?
Ken & Eric dive in and discuss the commercial pitch for this method of using fecal DNA vs visual inspection of the colon and what actually might be overlooked for the unsuspecting patient who is trying to remain healthy.
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Bonus Notes covered in this episode:
Does Cologuard detect polyps?
Yes, Cologuard can detect polyps. However, the detection of large polyps (the precursors to colon cancer) is less than half as accurate as a colonoscopy.
Is the Cologuard test as effective as a colonoscopy?
No, the Cologuard test is not as effective as a colonoscopy. Detecting and removing polyps is critical to colon cancer prevention, and Cologuard only detects large precancerous polyps 42% of the time. A colonoscopy detects the same polyps 95% of the time and they are removed during the same procedure.
What does Cologuard detect?
Cologuard can detect 92% of cancers and 42% of large precancerous polyps, the precursor to colon cancer.
What does it mean if your Cologuard test is positive?
If the Cologuard test is positive, it may mean that colon cancer or polyps are present. After a positive Cologuard test a colonoscopy is required for a definitive answer. The Cologuard test has a 13% false-positive rate, which means 1 in 10 positive tests will incorrectly identify cancer or polyps.
Does Cologuard detect cancer?
Yes, the Cologuard test can detect cancer 92% of the time. However, prevention of colon cancer is better than identifying it once you have it. The best way to prevent colon cancer is by identifying and removing precancerous polyps that don’t turn into cancer later. Cologuard only finds 42% of large, dangerous polyps that can turn into colon cancer.
Can patients use Cologuard instead of a colonoscopy?
Cologuard is not designed to be a replacement for a colonoscopy, even though advertisements may suggest otherwise. 58% of the time, dangerous precancerous polyps are not detected with Cologuard, which is significantly less effective than a colonoscopy. However, Cologuard may be an option for some patients who insist on not getting a colonoscopy or those not healthy enough to have a colonoscopy. Even a 42% chance of detection is better than no detection at all.
References for this episode:
Uptodate.com- colon cancer screening guidelines
Itzkowitz SH, Ahlquist DA. The case for a multitarget stool DNA test: a closer look at the cost effectiveness model. Gastroenterology. 2017;152(6):1620–1621
Johnson DH, Kisiel JB, Burger KN, et al. Multitarget stool DNA test: clinical performance and impact on yield and quality of colonoscopy for colorectal cancer screening. Gastrointest Endosc. 2017;85(3):657–665.e1.
Zauber A, Knudsen A, Rutter CM, et al. Evaluating the Benefits and Harms of Colorectal Cancer Screening Strategies: A Collaborative Modeling Approach. AHRQ Publication No. 14-05203-EF-2. Rockville, MD: Agency for Healthcare Research and Quality; October 2015.
Knudsen AB, Zauber AG, Rutter CM, et al. Estimation of Benefits, Burden, and Harms of Colorectal Cancer Screening Strategies: Modeling Study for the US Preventive Services Task Force. JAMA 2016; 315:2595.
Cost-effectiveness of a multitarget stool DNA test for colorectal cancer screening of Medicare beneficiaries
Steffie K. Naber ,Amy B. Knudsen ,Ann G. Zauber,Carolyn M. Rutter,Sara E. Fischer,Chester J. Pabiniak,Brittany Soto,Karen M. Kuntz,Iris Lansdorp-Vogelaar
Rex DK, Boland CR, et al. Colorectal cancer screening: Recommendations for physicians and patients from the U.S. Multi-Society Task Force on Colorectal Cancer. GI Endosc. 2017; 86(1):18-33.
Do you or a loved one suffer from IBD such as Crohn’s or Colitis? The world does not have to change for the worse!
Get in here and meet Dane Johnson, founder of Crohn’s Colitis Lifestyle, and END the suffering.
Dane is the founder of CrohnsColitisLifestyle inspired by his life-threatening battle with Crohn’s/Colitis, which he reversed using natural practice. As a Board Certified Nutritionist and one of the most successful Crohn’s/Colitis coaches in the world, he has helped thousands around the world find their unique answer to IBD while building a community of supporters, doctors and healers!
He brings the receipts! Even if you only hear the intro to this episode, you have to check out his page:
https://crohnscolitislifestyle.com/testimonials/
Join Ken and Eric as they learn about the path Dane forged to take control of his life.
Our tax dollars should not be used to create food sources engineered to make us sicker in exchange for enriching a select few industries.
But that is what is happening.
So how does this play into what RFK Jr. (Robert Kennedy, Jr.) has planned for the county? Why has he suspended his campaign to surprisingly join forces with President Trump? How serious is the threat of a growing chronic disease epidemic for future generations?
Ken & Eric take the latest news of RFK’s announcement and describe what they believe can be affected in this latest episode!
Full Clips for reference:
RFK Jr Statement
RFK Jr at Donald Trump Rally
Casey Means, MD & Calley Means with Tucker Carlson
https://tuckercarlson.com/tucker-show-casey-calley-means
Ken & Eric give a quick rundown of activities from the summer and a quick update on KBMD & GCP!
Purchase Atrantil & Atrantil Pro here: https://www.kbmdhealth.com/#shop
Chicago Mayor Brandon Johnson has proposed replacing the lost anchor grocery chains of Wal-Mart, Whole Foods, and others with city owned grocery stores.
A lack of law enforcement has resulted in rampant theft and shoplifting from several retailers in Chicago. These losses have resulted in many retailers including grocery stores in shuttering their doors and closing down.
This leaves many questions.
Who chooses the pricing? Who vets food quality? How big of a selection will be made available? Will government run grocery result in poor service like many public service exchanges currently (motor vehicle, permitting etc.) How can new brands effectively service and be distributed once established brands are afforded lobbying power?
What are your thoughts?
https://nypost.com/2023/09/18/chicago-mayor-considers-creating-city-owned-grocery-stores/
No idea why someone with these thoughts is comfortable using the term “ethicist”. Denying people the nutritional value of healthy meat is anything but ethical.
JUST COMMENT BELOW to SUBMIT OR EMAIL! Shari Guess is the host of the "Heavily Metalled Podcast". Shari almost died from severe allergies due to metal hypersensitivity after a litany of orthopedic surgeries, all performed within a few short years, which implanted a large amount of metal & dental hardware.
At the time she got sick, she was working as a full-time Realtor and attending college, studying pre-med, hoping to eventually become a P.A.
After being bedridden for nearly 3 years and furiously researching everything she could to help find out the cause of her severe systemic symptoms, she had a lucky break in the case and was able to connect the dots with all of her symptoms. Suddenly everything made sense!
Shari has undergone 4 surgeries to date to remove and revise hardware, with two more scheduled this year. These surgeries have restored her to near-full health as the symptoms related to her metal allergies began to subside by leaps and bounds immediately following the procedures.
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